Plantago major treatment enhanced innate antioxidant activity in experimental acetaminophen toxicity
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چکیده
منابع مشابه
Antioxidant properties and Glutathione S-transferases inhibitory activity of Alchornea cordifolia leaf extract in Acetaminophen toxicity
Paracetamol (acetaminophen, PCM) is a widely used over-the-counter analgesic and antipyretic drug. Intake of a large dose of PCM may result in severe hepatic necrosis. Oxidative stress is mediated by oxidative capacities of the PCM metabolite (N-acetyl-para-benzo quinoneimine, NAPQI), which covalently binds to proteins and other macromolecules to cause cellular damage. At low doses, NAPQI is ...
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The aim of the present study was to evaluate the effect of troxerutin (TXN) on Nickel (Ni) toxicity by using rats and in vitro model. Ni toxicity induced in male albino wistar rats (20 mg/kg body weight (b.w) was administered orally for 20 days). TXN was administered orally (100 mg/kg (b.w) for 20 days with administration of Ni. The toxic effect of Ni and the action of TXN was measure by determ...
متن کاملIn -vivo andIn -vitro antioxidant activity of Troxerutin on Nickel induced toxicity in Experimental Rats
The aim of the present study was to evaluate the effect of troxerutin (TXN) on Nickel (Ni) toxicity by using rats and in vitro model. Ni toxicity induced in male albino wistar rats (20 mg/kg body weight (b.w) was administered orally for 20 days). TXN was administered orally (100 mg/kg (b.w) for 20 days with administration of Ni. The toxic effect of Ni and the action of TXN was measure by determ...
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Hepatic injury induces inflammatory process and cell necrosis. Plantago major is traditionally used for various diseases. This study aimed to determine the anti-inflammatory property of P. major leaf extracts on inflammatory reaction following acetaminophen (APAP) hepatotoxicity. Thirty male Sprague-Dawley rats were divided into 5 groups, namely, normal control (C), APAP, aqueous (APAP + AQ), m...
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Plantago L. genus (Plantaginaceae) includes a large number of species differing in salt tolerance; many of them are adapted to live in saline environments, thus making the genus Plantago a good model for comparative studies about responses to salinity stress (1). Plantago genus includes species well-known as medicinal plants and others can be used for food and animal feeding (P. coronopus, P. l...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Biomedicine
سال: 2015
ISSN: 2221-1691
DOI: 10.1016/j.apjtb.2015.06.013